Welcome to UChicago PCCM Research!
Research defining the mechanisms, diagnosis, and treatment of lung disease and critical illness is a central mission of our group. This research is conducted in our clinical facilities as well as our basic research laboratories. Investigators are actively engaged in studying lung biology and cellular function related to critical illness, using techniques of cell and molecular biology, immunology, and genetics. Large and innovative clinical studies are also in place, with questions related to diagnosis and management of diverse diseases answered by accomplished clinical scientists observing individual patients and patient populations.
The strength of our research enterprise derives from the high degree of collaboration between basic and clinical scientists, and the joining of faculty and research associates with diverse training, expertise, and interests. The PhD, MD, and MD-PhD investigators in our group sustain this multi-faceted and dynamic approach to biomedical research. The essence of this activity is to ask important questions, and to answer them with whatever means are necessary—often employing the means of both clinical and basic science. The flow of ideas and findings is from bedside to bench and back, with each discovery adding to new questions requiring creative approaches to answer them. This exciting atmosphere provides abundant learning opportunities for students at every level of training, and we have successfully incorporated college, medical, and graduate students; post-doctoral scientists; residents; and fellows in our many programs.
News
SOFA doesn’t accurately predict mortality.. new pub by PCCM grads Miller and Han in the Parker group!
Accuracy of the Sequential Organ Failure Assessment Score for In-Hospital Mortality by Race and Relevance to Crisis Standards of Care
Question Is reliance on the Sequential Organ Failure Assessment (SOFA) score to estimate the risk of in-hospital mortality associated with bias against Black patients in Crisis Standards of Care (CSC)?
Findings In this cohort study of 95 549 patients in the intensive care unit, in-hospital mortality was lower among Black patients compared with White patients who had equivalent SOFA scores. This overestimation of mortality risk for Black patients was associated with deprioritization of Black patients in CSC.
Meaning This study’s findings that SOFA is associated with overestimated mortality among Black patients compared with White patients suggest that CSC are associated with systematic deprioritization of Black patients.
UC PCCM Fellowship Graduation, 2021!
Congratulations to Susan Han, MD, Catherine (Katie) Lee, MD, and William Dwight Miller, MD, for finishing their fellowship!
We wish them happiness and success, and will miss them all!
Highlighted works by these fabulous people to follow!